Santiago Metropolitan Region Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Santiago Metropolitan Region Vacation

When it's time for a break, book a Santiago Metropolitan Region vacation package. Get ready to enjoy nature, dining, culture, and more in this exciting destination. Begin your trip to Santiago Metropolitan Region with a couple of days in Santiago visiting popular sights like Plaza de Armas and Barrio París-Londres. Buin is another city that lures travellers from far and wide. Viña Santa Rita and Vina Haras de Pirque are two of the top places to see in this destination. From the instant you book your Santiago Metropolitan Region vacation to the second you come back home, Expedia has you covered each step of the way.

Top vacation destinations in Santiago Metropolitan Region

FlightsFlightsHotelsHotels

Santiago

Santiago
Hot springs of Valle Colina in the Cajon del Maipo, Cordillera de los Andes in Santiago, Chile
FlightsFlightsHotelsHotels

Colina

Colina

Where to stay in Santiago Metropolitan Region

Find the best Santiago Metropolitan Region areas and neighborhoods for the activities you enjoy most. Learn more about Santiago Metropolitan Region
Learn more about Santiago Metropolitan Region
Photo by Maria Isabel
Open Photo by Maria Isabel

Providencia

Boasting high-rise apartments and elegant houses, this area offers access to Cerro San Cristóbal with its Virgin Mary statue, Metropolitan Zoo, and the Teleférico. Explore the nearby bohemian Barrio Bellavista, home to artists and performers.
A city park with a fountain, trees, and modern buildings in the background.

Las Condes

Cafes, shopping, and mountain views highlight some notable features of Las Condes. Make a stop by Alto Las Condes or KidZania Santiago while you're visiting, and jump aboard the metro at Hernando de Magallanes Station or Manquehue Station to get around town.

Downtown Santiago

Central to Santiago Metropolitan Region, this commune boasts the oldest part of the city, including downtown and major government infrastructure like La Moneda palace.
Vintage Cerro Santa Lucia in Downtown Santiago, Chile.; Shutterstock ID 425476435

Lastarria

Visit this central Santiago neighborhood to relax on the lawns of Forest Park, eat in one of its many restaurants and browse weekend antique fairs.

Vitacura

Boasting Santiago's most exclusive shopping street, Avenida Alonso de Córdova, with luxury boutiques like Louis Vuitton and Armani, this upscale area is also home to elite private schools and the Gliders Club. Easily accessible via Costanera Norte toll-way.

Santiago Metropolitan Region Hotel Deals

Holiday Inn Santiago - Airport Terminal by IHG

Holiday Inn Santiago - Airport Terminal by IHG

4 out of 5
Armando Cortinez Norte 2150 Santiago Region Metropolitana
Fully refundable
The price is CA $183 per night from Jun 28 to Jun 29
CA $183
CA $197 total
Jun 28 - Jun 29
9/10 Wonderful! (1,494 reviews)
"Super convenient hotel right at the domestic terminal in Santiago"

Reviewed on Jun 24, 2026

Holiday Inn Santiago - Airport Terminal by IHG
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $368 per night from Jul 3 to Jul 4
CA $368
CA $368 total
Jul 3 - Jul 4
Mandarin Oriental, Santiago
Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
The price is CA $109 per night from Jun 29 to Jun 30
CA $109
CA $109 total
Jun 29 - Jun 30
8.2/10 Very good! (698 reviews)
"I asked for a desk chair and they didn’t have one, gave me an old uncomfortable chair that didn’t swivel, I asked for an iron and it didn’t work, not hot enough, they say parking included, but you have to walk like 4 blocks it’s not on site. Some of the staff were not welcoming, will never stay here ..."

Reviewed on Jun 10, 2026

Almacruz Hotel y Centro de Convenciones
See all 2,675 properties in Santiago Metropolitan Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Santiago Metropolitan Region vacation package cost?
We make it simple to explore the world, with Santiago Metropolitan Region packages starting from as little as . You'll have the flexibility to combine your preferred hotels, airlines and car rental. For the ultimate escape, why not add a couple of activities and tours to your travel itinerary?
How do I get a cheap travel package to Santiago Metropolitan Region?
Bundle your bookings with Expedia to save on your next big adventure. With over 550 partner airlines and 1,000,000 hotels throughout the world, your Santiago Metropolitan Region vacation package can be tailored exactly to suit your budget. With all that extra cash, why not include one or more exciting tours and activities? It's an easy way to unlock even more discounts. Your dream vacation in Santiago Metropolitan Region is closer than you thought!
Where should I stay in Santiago Metropolitan Region?
If you're eager to explore Palacio de la Moneda and San Cristobal Hill, Santiago is the destination for you.
What are the top hotels in Santiago Metropolitan Region?
Check out Holiday Inn Santiago - Airport Terminal, an IHG Hotel and La Quinta by Wyndham Santiago Aeropuerto. They're the first choice for many travelers to Santiago. If Lo Barnechea features on your itinerary, ICON Hotel and Radisson Blu Plaza El Bosque Santiago are both popular options.
How far in advance should I book my Santiago Metropolitan Region vacation?
It depends on the airline, but you can usually compare international fares on Expedia up to 12 months in advance. While it's advisable to book ahead of time, lucky travelers will occasionally score a cheaper flight just weeks prior to the date of departure.
What does an Expedia Santiago Metropolitan Region travel package include?
Expedia has everything you need to organize your Santiago Metropolitan Region escape, but what goes into your package is your choice. Pick from a combination of rental cars, flights and hotels. Chasing a few activities to keep you busy? Once you've made your booking, you can add them on too. Whatever your style or budget, there's a package deal to suit your needs.
What should I know before booking a Santiago Metropolitan Region travel package?
You'll land great savings when you bundle your flights, hotels and rental cars into a travel package. Not just that, booking everything in one spot makes trip planning easier. So why waste your money or time? Whether you're putting together a ritzy city getaway or a budget family adventure, have a look at our vacation packages today.
Can I choose my airline with a Santiago Metropolitan Region Expedia vacation package?
With a vacation package, you're the boss. Whether you're looking to fly to Santiago Metropolitan Region in coach or first class, simply pick from the available airline options. Expedia has access to more than 550 partner airlines throughout the world.
If I'm not able to travel, can I cancel my Santiago Metropolitan Region vacation package?
Yes, you can. We understand that things don't always go to plan, so we're here to help if you need to make changes to your Santiago Metropolitan Region vacation package. You may be able to change or cancel your itinerary for free if you've booked within 24 hours. Your airline, hotel or car rental company may impose a fee if you booked more than 24 hours ago. Have a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the nitty-gritty on change fees.

Stay near popular Santiago Metropolitan Region attractions

Photo by Maria Isabel
Open Photo by Maria Isabel

Costanera Center

9.0/5 (1,666 reviews)
Discover hundreds of retail outlets, cafés and restaurants, and see one of South America’s tallest buildings at this modern retail and business center.
See properties

What to do in Santiago Metropolitan Region

Viña Del Mar-Valparaiso -Casablanca -Reñaca-Oceanic Rock-Concon

Viña Del Mar-Valparaiso -Casablanca -Reñaca-Oceanic Rock-Concon

CA $57
per adult
Viña Del Mar-Valparaiso -Casablanca -Reñaca-Oceanic Rock-Concon
Santiago: Concha y Toro and Undurraga Vineyards Tour

Santiago: Concha y Toro and Undurraga Vineyards Tour

CA $105
per adult
100% of travellers recommend
Santiago: Concha y Toro and Undurraga Vineyards Tour
Inca Lagoon in Portillo

Inca Lagoon in Andes Mountain Range - Visit Local Vineyard with Tasting included

CA $109
per adult
92% of travellers recommend
Inca Lagoon in Andes Mountain Range - Visit Local Vineyard with Tasting included
See all activities in Santiago Metropolitan Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.